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Interface BioActive Bone Graft

Interface Bioactive Bone GraftInterface BioActive Bone Graft is a synthetic bone graft for use in the repair of osseous defects. Through a proprietary process, Interface BioActive Bone Graft is made of the highest quality irregular synthetic granules of bioactive glass. These synthetic bioactive granules are optimally sized for ease of administration. When implanted in living tissue, the Interface BioActive Bone Graft material undergoes a time dependent surface modification. The surface reaction results in the formation of a calcium phosphate layer, which is equivalent in composition and structure to the hydroxyapatite found in bone mineral. The biological apatite layer of the granules provides an osteoconductive scaffold for the generation of new osseous tissue. New bone infiltrates around the granules allowing the repair of the defect as the granules are absorbed.

The benefits throughout each stage of the process include:

Innovative Design

  • Supplied as irregular synthetic granules of bioactive glass sized from 200-420 microns
  • Interface BioActive Bone Graft is designed for the repair of osseous defects in orthopedic applications

Bioactive

  • When implanted in living tissue, the material undergoes a time dependent surface modification
  • The biological apatite layer of the granules provides a scaffold for the generation of new osseous tissue

Patented Technology1

  • The narrow particle size distribution of 200-420 microns is designed to provide enhanced performance benefits
  • The patented Interface BioActive Bone Graft technology is designed for a faster speed of bone fill than glass particles having a broader size distribution

Safe and Consistent

  • Interface is a safe alternative to freeze-dried or human bone-based products
  • Consistent bioactive glass composition
  • Can be used independent of blood type or other typing restrictions

Convenient Packaging

  • Conveniently packaged in a sterile single-use vial
  • Stored within a hermetically sealed foil pouch to ensure product sterility prior to implantation

Composition

  • The elemental composition of Interface BioActive Bone Graft is Si, Ca, Na and P
  • Interface BioActive Bone Graft conforms to ASTM specification F1538 for 45S5 bioactive glass

1United States Patent 6,228,386 B1